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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Mercurial diuretic ： ウィキペディア英語版 Mercurial diuretic Mercurial diuretics are a form of renal diuretic containing mercury. Although previously widely used, they have largely been superseded by safer diuretics such as thiazides, and are hardly used anymore. ==History and mechanism== Inorganic mercury compounds, such as mercury(I)chloride (calomel), were found to have diuretic properties when they were used to treat syphilis.〔 〕 Proposed use of these compounds date back at least to the 16th century, shortly after the beginning of the syphilis epidemic in 1497 following Colombus' return to Europe. Mercurial diuretics cause diuresis by reducing the reabsorption sodium in the ascending loop of Henle, thus causing more water being delivered to the distal convoluted tubule. Unfortunately, earlier physicians misconstrued hallmark symptoms of mercury poisoning such as excessive salivation as signs of mercury's efficacy, including up until the early 1960s when the use of mercurial diuretics were halted in medicine. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Mercurial diuretic」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.